CLINICAL RESEARCH
Prevalence and distribution of colonic diverticulosis in patients undergoing colonoscopy. Four years’ experience from a single center in Warsaw
 
More details
Hide details
 
Submission date: 2016-03-21
 
 
Final revision date: 2016-04-23
 
 
Acceptance date: 2016-04-24
 
 
Publication date: 2016-05-23
 
 
Arch Med Sci Civil Dis 2016;1(1):30-35
 
KEYWORDS
TOPICS
Other
 
ABSTRACT
Introduction: Data on the prevalence of diverticulosis in the Polish population are limited. Most patients are asymptomatic, so it is difficult to estimate the scale of the problem in the population. The aim of this study was to determine the prevalence of colonic diverticulosis in Polish adults based on a sample from a single, medium-sized endoscopy department. The secondary objective was to assess the distribution of diverticula in the colon and their association with sex and age.
Material and methods: Between 2010 and 2014 a total of 6087 consecutive patients (age range: 18–94 years, mean age: 54 years) underwent colonoscopy in the department. 1981 patients were excluded from the study due to incomplete examination, colorectal surgery or inadequate preparation resulting in insufficient visibility. The remaining 4106 patients were included in the study (1648 – male, 2458 – female). Data concerning age, sex, and presence and location of diverticula were studied in a retrospective manner.
Results: Diverticula were found in 29.6% of all participants (29.4% – male, 29.8% – female). 0.5% of patients (0.7% – male, 0.5% – female) had right-sided diverticulosis, while in 23.7% (23.4% – male, 24.0% – female) diverticula were located in the left colon only. Pancolonic diverticulosis was present in 4.0% (4.0% – male, 4.0% – female). For all statistical calculations p  0.05. The prevalence of diverticulosis increased with age. No difference was noted between men and women.
Conclusions: In the studied sample, diverticula predominantly occurred in the sigmoid and descending colon. Their prevalence and distribution were similar to other Caucasian populations.
REFERENCES (35)
1.
Etzioni DA, Mack TM, Beart RW Jr, Kaiser AM. Diverticulitis in the United States: 1998–2005: changing patterns of disease and treatment. Ann Surg 2009; 249: 210-7.
 
2.
West AB. The pathology of diverticulosis: classical concepts and mucosal changes in diverticula. J Clin Gastroenterol 2006; 40: 126-131.
 
3.
Shahedi K, Fuller G, Bolus R, et al. Long-term risk of acute diverticulitis among patients with incidental diverticulosis found during colonoscopy. Clin Gastroenterol Hepatol 2013; 11: 1609-13.
 
4.
Lewis LM, Banet GA, Blanda M, Hustey FM, Meldon SW, Gerson LW. Etiology and clinical course of abdominal pain in senior patients: a prospective, multicenter study. J Gerontol A Biol Sci Med Sci 2005; 60: 1071-6.
 
5.
Reddy VB, Longo WE. The burden of diverticular disease on patients and healthcare systems. Gastroenterol Hepatol 2013; 9: 21-7.
 
6.
Burkitt D. Diverticular disease of the colon epidemiological evidence relating it to fibre-depleted diets. Trans Med Soc Lond 1973; 89: 81-4.
 
7.
Floch MH, Bina I. The natural history of diverticulitis: fact and theory. J Clin Gastroenterol 2004; 38: 2-7.
 
8.
Peery AF, Sandler RS, Ahnen DJ, et al. Constipation and a low-fiber diet are not associated with diverticulosis. Clin Gastroenterol Hepatol 2013; 11: 1622-7.
 
9.
Ünlü C, Daniels L, Vrouenraets BC, Boermeester MA. A systematic review of high-fibre dietary therapy in diverticular disease. Int J Colorectal Dis 2012; 27: 419-27.
 
10.
Burgell RE, Muir JG, Gibson PR. Pathogenesis of colonic diverticulosis: repainting the picture. Clin Gastroenterol Hepatol 2013; 11: 1628-30.
 
11.
Wess L, Eastwood MA, Wess TJ, Busuttil A, Miller A. Cross linking of collagen is increased in colonic diverticulosis. Gut 1995; 37: 91-4.
 
12.
Touzios JG, Dozois EJ. Diverticulosis and acute diverticulitis. Gastroenterol Clin N Am 2009; 38: 513-25.
 
13.
Reichert MC, Lammert F. The genetic epidemiology of diverticulosis and diverticular disease: emerging evidence. United Eur Gastroenterol J 2015; 3: 409-18.
 
14.
Song JH, Kim YS, Lee JH, et al. Clinical characteristics of colonic diverticulosis in Korea: a prospective study. Korean J Intern Med 2010; 25: 140-6.
 
15.
Tănase I, Păun S, Stoica B, Negoi I, Gaspar B, Beuran M. Epidemiology of the diverticular disease – systematic review of the literature. Chirurgia (Bucur) 2015; 110: 9-14.
 
16.
Blachut K, Paradowski L, Garcarek J. Prevalence and distribution of the colonic diverticulosis. Review of 417 cases from Lower Silesia in Poland. Rom J Gastroenterol 2004; 13: 281-5.
 
17.
Loffeld RJ, Van Der Putten AB. Diverticular disease of the colon and concomitant abnormalities in patients undergoing endoscopic evaluation of the large bowel. Colorectal Dis 2002; 4: 189-92.
 
18.
Everhart JE, Ruhl CE. Burden of digestive diseases in the United States part II: lower gastrointestinal diseases. Gastroenterology 2009; 3: 741-54.
 
19.
Kang JY, Dhar A, Pollok R, et al. Diverticular disease of the colon: ethnic differences in frequency. Aliment Pharmacol Ther 2004; 19: 765-9.
 
20.
Lin OS, Soon MS, Wu SS, Chen YY, Hwang KL, Triadafilopoulos G. Dietary habits and right-sided colonic diverticulosis. Dis Colon Rectum 2000; 43: 1412-8.
 
21.
Manousos O, Day NE, Tzonou A, et al. Diet and other factors in the aetiology of diverticulosis: an epidemiological study in Greece. Gut 1985; 26: 544-9.
 
22.
Gear JS, Ware A, Fursdon P, et al. Symptomless diverticular disease and intake of dietary fibre. Lancet 1979; 1: 511-4.
 
23.
Strate LL. Diverticulosis and dietary fiber: rethinking the relationship. Gastroenterology 2012; 142: 205-7.
 
24.
Hodgson WJ. The placebo effect. Is it important in diverticular disease? Am J Gastroenterol 1977; 67: 157-62.
 
25.
Brodribb AJ. Treatment of symptomatic diverticular disease with a high-fibre diet. Lancet 1977; 1: 664-6.
 
26.
Ornstein MH, Littlewood ER, Baird IM, Fowler J, North WR, Cox AG. Are fibre supplements really necessary in diverticular disease of the colon? A controlled clinical trial. Br Med J (Clin Res Ed) 1981; 282: 1353-6.
 
27.
Jun S, Stollman N. Epidemiology of diverticular disease. Best Pract Res Clin Gastroenterol 2002; 16: 529-42.
 
28.
Warner E, Crighton EJ, Moineddin R, Mamdani M, Upshur R. Fourteen-year study of hospital admissions for diverticular disease in Ontario. Can J Gastroenterol 2007; 21: 97-9.
 
29.
Annibale B, Lahner E, Maconi G, et al. Clinical features of symptomatic uncomplicated diverticular disease a multicenter Italian survey. Int J Colorectal Dis 2012; 27: 1151-9.
 
30.
Granlund J, Svensson T, Olén O, et al. The genetic influence on diverticular disease – a twin study. Aliment Pharmacol Ther 2012; 35: 1103-7.
 
31.
Strate LL, Erichsen R, Baron JA, et al. Heritability and familial aggregation of diverticular disease: a population-based study of twins and siblings. Gastroenterology 2013; 144: 736-42.
 
32.
Connelly TM, Bert AS, Hegarty JP, et al. The TNFSF15 gene single nucleotide polymorphism rs7848647 is associated with surgical diverticulitis. Ann Surg 2014; 259: 1132-7.
 
33.
Pepin M, Schwarze U, Superti-Furga A, Byers PH. Clinical and genetic features of Ehlers-Danlos syndrome type IV, the vascular type. N Engl J Med 2000; 342: 673-80.
 
34.
Eliashar R, Sichel JY, Biron A, Dano I. Multiple gastrointestinal complications in Marfan syndrome. Postgrad Med J 1998; 74: 495-7.
 
35.
Pourfarziani V, Mousavi-Nayeeni SM, Ghaheri H, et al. The outcome of diverticulosis in kidney recipients with polycystic kidney disease. Transplant Proc 2007; 39: 1054-6.
 
ISSN:2451-0637
Journals System - logo
Scroll to top