CLINICAL RESEARCH
Have malignancy rates increased in thyroidectomy cases?
1
Department of General Surgery, Malatya Turgut Özal University, School of Medicine, Turkey
2
Department of General Surgery, Balıkesir University,School of Medicine, Turkey
3
Department of General Surgery, Fethi Sekin City Hospital, Turkey
4
Department of General Surgery, Nizip State Hospital, Turkey
5
Department of General Surgery, Kahramanmaraş Sütçü İmam University School of Medicine, Turkey
6
Department of Internal Medicine, Malatya Training and Research Hospital, Turkey
Submission date: 2021-02-07
Acceptance date: 2021-03-27
Publication date: 2021-04-20
Arch Med Sci Civil Dis 2021;6(1):46-49
KEYWORDS
TOPICS
ABSTRACT
Introduction:
This study aims to review thyroidectomy cases performed by a single surgeon in a single centre during the course of 1 year, to determine if the malignancy rate increased, and to compare the results with the literature.
Material and methods:
We retrospectively evaluated data of patients who underwent thyroidectomy between August 2018 and August 2019 in the General Surgery Clinic of our hospital. The malignancy rate was calculated and analysed according to the demographic data of the patients (gender and age), preoperative thyroid nodule sizes, and postoperative pathological mass sizes. Also, age, preoperative nodule size, and tumour size were all evaluated according to gender.
Results:
There were a total of 60 patients (14 (23%) male and 46 (77%) female). The pathology result revealed 16 (26.7%) malignant and 44 (73.3%) benign biopsies. The mean age was 46.72 ±12.08 years (20–74). We found that age, preoperative nodule size (cm), pathological tumour size (cm), and thyroid function tests were not significantly associated with malignancy. However, when age, preoperative nodule size, and tumour sizes were evaluated according to gender, it was found that tumour sizes were significantly larger in men than in women (p < 0.001). In addition, the mean age of male patients was higher than that of women (p = 0.025).
Conclusions:
The malignancy rate has increased in the thyroidectomies performed in our centre. This finding is consistent with relevant studies from the last 30 years. Therefore, it is likely that clinicians will continue to handle an increased number of thyroid malignancies.
This study aims to review thyroidectomy cases performed by a single surgeon in a single centre during the course of 1 year, to determine if the malignancy rate increased, and to compare the results with the literature.
Material and methods:
We retrospectively evaluated data of patients who underwent thyroidectomy between August 2018 and August 2019 in the General Surgery Clinic of our hospital. The malignancy rate was calculated and analysed according to the demographic data of the patients (gender and age), preoperative thyroid nodule sizes, and postoperative pathological mass sizes. Also, age, preoperative nodule size, and tumour size were all evaluated according to gender.
Results:
There were a total of 60 patients (14 (23%) male and 46 (77%) female). The pathology result revealed 16 (26.7%) malignant and 44 (73.3%) benign biopsies. The mean age was 46.72 ±12.08 years (20–74). We found that age, preoperative nodule size (cm), pathological tumour size (cm), and thyroid function tests were not significantly associated with malignancy. However, when age, preoperative nodule size, and tumour sizes were evaluated according to gender, it was found that tumour sizes were significantly larger in men than in women (p < 0.001). In addition, the mean age of male patients was higher than that of women (p = 0.025).
Conclusions:
The malignancy rate has increased in the thyroidectomies performed in our centre. This finding is consistent with relevant studies from the last 30 years. Therefore, it is likely that clinicians will continue to handle an increased number of thyroid malignancies.
REFERENCES (27)
1.
Erbil Y, Barbaros U, Salmaslioglu A, Yanik BT, Bozbora A, Ozarmagan S. The advantage of near-total thyroidectomy to avoid postoperative hypoparathyroidism in benign multinodular goiter. Langenbecks Arch Surg 2006; 391: 567-73.
2.
Uludağ M, İşgör A. Scarless thyroidectomy: transoral endoscopic thyroidectomy by vestibular approach. Med Bull Sisli Etfal Hospital 2017; 51: 169-83.
3.
Cottrill EE, Funk EK, Goldenberg D, Goyal N. Transoral thyroidectomy using a flexible robotic system: a preclinical cadaver feasibility study. Laryngoscope 2019; 129: 1482-7.
4.
Gardner IH, Doherty GM, McAneny D. Intraoperative nerve monitoring during thyroid surgery. Curr Opin Endocrinol Diabetes Obes 2016; 23: 394-9.
5.
Dağlı AF, Artaş G. The prevalence of thyroid cancer and sub-types in Elazığ: a five year experience. İnönü Üniversitesi Sağlık Hizmetleri Meslek Yüksekokulu Dergisi 2016; 4: 1-5.
6.
Şahin N, Üçer Ö. The incidence of thyroid cancer at thyroidectomy materials in Malatya. Dicle Med J 2013; 40: 570-3.
7.
Maturo A, Tromba L, De Anna L, et al. Incidental thyroid carcinomas. A retrospective study. G Chir 2017; 38: 94-101.
8.
Charles BF, et al. Schwartz’s principels of surgery. In: Thyroid, Parathyroid, Adrenal. Lal G, Clark HO (eds.).
10.
Townsend MC, et al. Sabiston Textbook of Surgery. In: Thyroid. Hanks BJ (ed.). Saunders Elsevier, Philadelphia 2004: 947-99.
11.
Kitahara CM, McCullough ML, Franceschi S, et al. Anthropometric factors and thyroid cancer risk by histological subtype: pooled analysis of 22 prospective studies. Thyroid 2016; 26: 306-18.
12.
Kitahara C, Gamborg M, Berrington A, Sørensen T, Baker J. Childhood height and body mass index were associated with risk of adult thyroid cancer in a large cohort study. Cancer Res 2014; 74: 235-42.
13.
Kitahara CM, Linet MS, Beane Freeman LE, et al. Cigarette smoking, alcohol intake, and thyroid cancer risk: a pooled analysis of five prospective studies in the United States. Cancer Causes Control 2012; 23: 1615-24.
14.
Almquist M, Johansen D, Björge T, et al. Metabolic factors and risk of thyroid cancer in the Metabolic Syndrome and Cancer Project (Me-Can). Cancer Causes Control 2011; 22: 743-51.
16.
Burgess J. Temporal trends for thyroid carcinoma in Australia: an increasing incidence of papillary thyroid carcinoma (1982–1997). Thyroid 2002; 12: 141-9.
17.
Colonna M, Grosclaude P, Remontet L, et al. Incidence of thyroid cancer in adults recorded by French cancer registries (1978–1997). Eur J Cancer 2002; 38: 1762-8.
18.
Davies L, Welch HG. Increasing incidence of thyroid cancer in the United States, 1973-2002. JAMA 2006; 295: 2164-7.
19.
Grodski S, Brown T, Sidhu S, et al. Increasing incidence of thyroid cancer is due to increased pathologic detection. Surgery 2008; 144: 1038-43.
20.
Enewold L, Zhu K, Ron E, et al. Rising thyroid cancer incidence in the United States by demographic and tumor characteristics, 1980–2005. Cancer Epidemiol Biomarkers Prev 2009; 18: 784-91.
21.
Rego-Iraeta A, Pérez-Méndez LF, Mantinan B, Garcia-Mayor RV. Time trends for thyroid cancer in northwestern Spain: true rise in the incidence of micro and larger forms of papillary thyroid carcinoma. Thyroid 2009; 19: 333-40.
22.
Simard EP, Ward EM, Siegel R, Jemal A. Cancers with increasing incidence trends in the United States: 1999 through 2008. CA Cancer J Clin 2012; 62: 118-28.
23.
Chen AY, Jemal A, Ward EM. Increasing incidence of differentiated thyroid cancer in the United States, 1988–2005. Cancer 2009; 115: 3801-7.
24.
Aschebrook-Kilfoy B, Ward MH, Sabra MM, Devesa SS. Thyroid cancer incidence patterns in the United States by histologic type, 1992–2006. Thyroid 2011; 21: 125-34.
25.
Pellegriti G, Frasca F, Regalbuto C, Squatrito S, Vigneri R. Worldwide increasing rate of thyroid cancer: update on epidemiology and risk factors. J Cancer Epidemiol 2013; 2013: 965212.
26.
Kitahara CM, Sosa JA. The changing incidence of thyroid cancer. Nat Rev Endocrinol 2016; 12: 646-53.
27.
Burgess JR. Temporal trends for thyroid carcinoma in Australia: an increasing incidence of papillary thyroid carcinoma (1982-1997). Thyroid 2002; 12: 141-9.
| ISSN: | 2451-0637 |
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