CLINICAL RESEARCH
COVID-19 implications at the Clinical University Center in Kosovo – Department of Pediatrics
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1
Department of Pediatric, University Clinical Center, Prishtina, Kosovo
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Faculty of Sciences, University of Sarajevo, Sarajevo, Bosnia and Herzegovina
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College UBT, Faculty of Pharmacy, Prishtina, Kosovo
Submission date: 2021-02-19
Acceptance date: 2021-05-29
Publication date: 2021-06-30
Arch Med Sci Civil Dis 2021;6(1):61-67
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ABSTRACT
Introduction:
In late December 2019, the first pneumonia cases of unknown origin were identified in Wuhan, the capital city of Hubei province in central China. While the most data are available for adult patients with COVID-19, limited reports analyze pediatric patients infected with SARS-CoV-2. The aim of the study was to describe the epidemiological and clinical characteristics of coronavirus disease (COVID-19) in patients at the Pediatric Clinical Center of Kosovo.
Material and methods:
This research is retrospective and includes data for the period from 8 July 2020 to 6 January 2021. In this study we obtained data from different documents and patients’ records, providing information regarding gender, age, number of cases, most frequent diagnosis, critical patients, etc.
Results:
Out of 69 pediatric patients hospitalized in the clinic during the seven months, 50 patients tested positive with COVID-19. The study sample represented an equal number of males and females (50/50), while the average age of the patients was 6 years. Based on the pediatric age groups, the study sample comprises 16 patients of the age groups of 1 month–2 years, 20 patients of the age group of 2–6 years; 4 patients of the age group of 6–12 years, and 10 patients of the age group of 12–18 years.
Conclusions:
Data suggest that pediatric cases of COVID-19 in adolescents have more severe symptoms than in the other age groups; however, in general children tend to cope much more easily with the virus than adults.
REFERENCES (19)
1.
Guan WJ, Ni ZY, Hu Y, et al. Clinical characteristics of coronavirus disease 2019 in China. N Engl J Med 2020; 382: 1708-20.
2.
Lai CC, Shih TP, Ko WC, Tang HJ, Hsueh PR. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): the epidemic and the challenges. Int J Antimicrob Agents 2020; 55: 105924.
3.
Guo YR, Cao QD, Hong ZS, et al. The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak – an update on the status. Mil Med Res 2020; 7: 11.
4.
World Health Organization. Coronavirus disease (COVID-19) Pandemic (2020). www.who.int/emergencies/diseases/novel-coronavirus-2019.
5.
Bung N, Krishnan SR, Bulusu G, Roy A. De novo design of new chemical entities (NCEs) for SARS-CoV-2 using artificial intelligence. ChemRxiv 2020; 10.26434/chemrxiv.11998347.
6.
Li F. Structure, function, and evolution of coronavirus spike proteins. Annu Rev Virol 2016; 3: 237-61.
7.
Cascella M, Rajnik M, Cuomo A, Dulebohn SC, Di Napoli R. Features, evaluation and treatment coronavirus (COVID-19). FL, USA, StatPearls. StatPearls Publishing 2020.
8.
Fehr AR, Perlman S. Coronaviruses: an overview of their replication and pathogenesis. In: Coronaviruses: Methods and Protocols. Maier H, Bickerton E, Britton P (eds). Humana Press 2015; 1-282.
9.
Ganyani T, Kremer C, Chen D, et al. Estimating the generation interval for coronavirus disease (COVID-19) based on symptom onset data, March 2020. Euro Surveill 2020; 25: 2000257.
10.
Mao R, Qiu Y, He JS, et al. Manifestations and prognosis of gastrointestinal and liver involvement in patients with COVID-19: a systematic review and meta-analysis. Lancet Gastroenterol Hepatol 2020; 5: 667-78.
11.
Levi M, Thachil J, Iba T, Levy JH. Coagulation abnormalities and thrombosis in patients with COVID-19. Lancet Haematol 2020; 7: 438-40.
12.
Long B, Brady WJ, Koyfman A, Gottlieb M. Cardiovascular complications in COVID-19. Am J Emerg Med 2020; 38: 1504-7.
13.
Mao L, Jin H, Wang M, et al. Neurologic manifestations of hospitalized patients with coronavirus disease 2019 inWuhan, China. JAMA Neurol 2020; 77: 683-90.
14.
Middeldorp S, Coppens M, van Haaps TF, et al. Incidence of venous thromboembolism in hospitalized patients with COVID-19. J Thromb Haemost 2020; 18: 1995-2002.
15.
Chen YT, Shao SC, Hsu CK, Wu IW, Hung MJ, Chen YC. Incidence of acute kidney injury in COVID-19 infection: a systematic review and meta-analysis. Crit Care 2020; 24: 346.
16.
Rodriguez-Morales AJ, Cardona-Ospina JA, Gutierrez-Ocampo E, et al.; Latin American Network of Coronavirus Disease 2019-COVID-19 Research (LANCOVID-19). Clinical, laboratory and imaging features of COVID-19: a systematic review and meta-analysis. Travel Med Infect Dis 2020; 34: 101623.
17.
Riphagen S, Gomez X, Gonzalez-Martinez C, Wilkinson N, Theocharis P. Hyperinflammatory shock in children during COVID-19 pandemic. Lancet 2020; 395: 1607-8.
18.
Godfred-Cato S, Bryant B, Leung J, et al. COVID-19-associated multisystem inflammatory syndrome in children – United States, March–July 2020. MMWR Morb Mortal Wkly Rep 2020; 69: 1074.
19.
Radia T, Williams N, Agrawal P, et al. Multi-system inflammatory syndrome in children and adolescents (MIS-C): a systematic review of clinical features and presentation. Pediatr Respir Rev 2020; doi: 10.1016/j.prrv.2020.08.001.